Myiasis in Neglected Cutaneous Squamous Cell Carcinoma of the Head and Neck: Review of Management and Current Protocol Recommendations

Golda Grinblat; Yulia Frenkel; Isaac Shochat; Andro Košec; Ayelet Midbari; Roman Rysin; Manjunath Dandinarasaiah; Itzhak Braverman; Yoram Wolf

doi:10.1097/01.ASW.0000752708.82300.a4

Myiasis in Neglected Cutaneous Squamous Cell Carcinoma of the Head and Neck: Review of Management and Current Protocol Recommendations

Adv Skin Wound Care. 2021 Jul 1;34(7):372-378. doi: 10.1097/01.ASW.0000752708.82300.a4.

Authors

Golda Grinblat¹, Yulia Frenkel, Isaac Shochat, Andro Košec, Ayelet Midbari, Roman Rysin, Manjunath Dandinarasaiah, Itzhak Braverman, Yoram Wolf

Affiliation

¹ Golda Grinblat, MD, is Senior Consultant, Otolaryngology and Head and Neck Surgery Department, Hillel Yaffe Medical Center, Hadera, Israel. Yulia Frenkel, MD, is Resident, Anesthesiology Department, Sheba Medical Center, Tel Aviv. Isaac Shochat, MD, is Resident, Otolaryngology and Head and Neck Surgery Department, Hillel Yaffe Medical Center. Andro Košec, MD, PhD, FEBORL-HNS, is Consultant Surgeon, Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center Sestre Milosrdnice, School of Medicine, University of Zagreb, Croatia. Ayelet Midbari, MD, is Unit Chief, Pain Relief Unit, Hillel Yaffe Medical Center. Roman Rysin, MD, is Pre-Resident, Plastic Surgery Department, Hillel Yaffe Medical Center. Manjunath Dandinarasaiah, MD, is Associate Professor, Karnataka Institute of Medical Sciences, Vidyanagar, Hubli, Karnataka, India. At the Hillel Yaffe Medical Center, Itzhak Braverman, MD, is Director, Otolaryngology and Head and Neck Surgery Department; and Yoram Wolf, MD, is Unit Chief, Plastic Surgery Department. Acknowledgments: The authors thank Mrs Shelly Rado, Registered Nurse of the Pain Unit at Hillel Yaffe Medical Center for her assistance in wound care. The authors have disclosed no financial relationships related to this article. Submitted June 17, 2020; accepted in revised form October 2, 2020.

PMID: 34125727
DOI: 10.1097/01.ASW.0000752708.82300.a4

Abstract

Objective: To propose a first-aid management protocol for myiasis in neglected cutaneous squamous cell carcinoma (SCC) in the ED based on a recent literature review.

Data sources: PubMed.

Study selection: Inclusion criteria were all series and case reports of primary/secondary cutaneous SCC with myiasis of the head and neck, including orbital SCC cases, published after 2005.

Data extraction: A total of 14 articles including 15 patients were included.

Data synthesis: Demographics, socioeconomic situation, site of the lesion, larvae species with bacterial suprainfection, and first-aid treatment options were discussed. Two representative cases are described.

Conclusions: Large, ulcerated, necrotic, myiasis-burdened SCC lesions in the head and neck area present a challenge for treatment, and to date, no consensus regarding first-aid management exists. The authors' proposed four-pillar first-aid management scheme may be a valid option to rapidly improve wound condition through disinfection, pain relief, and malodor and discharge eradication as a bridge to surgery.

Publication types

Review

MeSH terms

Aged
Aged, 80 and over
Female
Guidelines as Topic / standards
Humans
Male
Myiasis / etiology*
Myiasis / pathology
Squamous Cell Carcinoma of Head and Neck / complications*
Squamous Cell Carcinoma of Head and Neck / pathology
Time-to-Treatment