Mirau-type full-field optical coherence tomography with switchable partially spatially coherent illumination modes

Tuan-Shu Ho; Ming-Rung Tsai; Chih-Wei Lu; Hung-Sheng Chang; Sheng-Lung Huang

doi:10.1364/BOE.422622

Mirau-type full-field optical coherence tomography with switchable partially spatially coherent illumination modes

Biomed Opt Express. 2021 Apr 12;12(5):2670-2683. doi: 10.1364/BOE.422622. eCollection 2021 May 1.

Authors

Tuan-Shu Ho^{1

2}, Ming-Rung Tsai¹, Chih-Wei Lu¹, Hung-Sheng Chang¹, Sheng-Lung Huang^{1

3

4

5}

Affiliations

¹ Apollo Medical Optics, Ltd., Taipei 114, Taiwan.
² Correspondence regarding OCT system design questions should be sent to tuanshu@mdamo.com.
³ Graduate Institute of Photonics and Optoelectronics, National Taiwan University, Taipei 106, Taiwan.
⁴ Department of Electrical Engineering, National Taiwan University, Taipei 106, Taiwan.
⁵ Correspondence regarding light source questions should be sent to shaung@ntu.edu.tw.

Abstract

A crystalline-fiber-based Mirau-type full-field optical coherence tomography (FF-OCT) system utilizing two partially coherent illumination modes is presented. Using a diode-pumped Ti:sapphire crystalline fiber with a high numerical aperture, spatially-incoherent broadband emission can be generated with high radiance. With two modes of different spatial coherence settings, either deeper penetration depth or higher B-scan rate can be achieved. In a wide-field illumination mode, the system functions like FF-OCT with partially coherent illumination to improve the penetration depth. In a strip-field illumination mode, a compressed field is generated on the sample, and a low-speckle B-scan can be acquired by compounding pixel lines within.