Ortho C-H arylation of arenes at room temperature using visible light ruthenium C-H activation

Arunachalam Sagadevan; Anastasios Charitou; Fen Wang; Maria Ivanova; Martin Vuagnat; Michael F Greaney

doi:10.1039/d0sc01289k

Ortho C-H arylation of arenes at room temperature using visible light ruthenium C-H activation

Chem Sci. 2020 Apr 7;11(17):4439-4443. doi: 10.1039/d0sc01289k.

Authors

Arunachalam Sagadevan¹, Anastasios Charitou¹, Fen Wang¹, Maria Ivanova¹, Martin Vuagnat¹, Michael F Greaney¹

Affiliation

¹ School of Chemistry, The University of Manchester Oxford Road Manchester M13 9PL UK michael.greaney@manchester.ac.uk.

Abstract

A ruthenium-catalyzed ortho C-H arylation process is described using visible light. Using the readily available catalyst [RuCl₂(p-cymene)]₂, visible light irradiation was found to enable arylation of 2-aryl-pyridines at room temperature for a range of aryl bromides and iodides.