Biliary reconstruction after choledochal cyst resection: a systematic review and meta-analysis on hepaticojejunostomy vs hepaticoduodenostomy

Pediatr Surg Int. 2021 Oct;37(10):1313-1322. doi: 10.1007/s00383-021-04940-z. Epub 2021 Jun 11.

Abstract

Choledochal cysts are a rare pediatric biliary pathology. Excision of the extrahepatic cyst and restoration of biliary-enteric continuity through either hepaticoduodenostomy (HD) or Roux-en-Y hepaticojejunostomy (HJ) is the mainstay treatment. This study aims to determine if either method provides an advantage. Following PRISMA guidelines, a systematic review was conducted, identifying studies comparing hepaticojejunostomy to hepaticoduodenostomy in patients with choledochal cysts. Data were analyzed using Review Manager 5.3. Nine studies were included, operative time was shorter - 97.50 [- 172.31, - 22.69] p = 0.01 and bleeding reduced - 48.98 [- 88.25, - 9.71] p = 0.01 in HD. HD was associated with shorter length of stay 2.18 [- 3.87, - 0.50] p = 0.01 and similar cholangitis and reintervention rates. Time to a normal diet was similar between groups. Biliary reflux was seen more frequently in HD 19.14 [2.60, 140.63] p = 0.004. Complications such as leak and cholangitis were similar between groups. HD represents a viable alternative to HJ with various advantages such as shorter operative time, decreased bleeding and shorter length of hospital stay. Bile reflux remains a major limitation.Level of evidence IV.

Keywords: Biliary reconstruction; Choledocal cyst; Hepaticoduodenostomy; Hepaticojejunostomy.

Publication types

  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Anastomosis, Roux-en-Y
  • Anastomosis, Surgical
  • Biliary Tract Surgical Procedures*
  • Child
  • Choledochal Cyst* / surgery
  • Humans
  • Retrospective Studies