Pediatric long-COVID: An overlooked phenomenon?

Pediatr Pulmonol. 2021 Aug;56(8):2495-2502. doi: 10.1002/ppul.25521. Epub 2021 Jun 8.

Abstract

Background: Long-COVID is a well-documented multisystem disease in adults. Far less is known about long-term sequelae of COVID in children. Here, we report on the occurrence of long-COVID in Dutch children.

Patients and methods: We conducted a national survey asking Dutch pediatricians to share their experiences on long-COVID in children. We furthermore describe a case series of six children with long-COVID to explore the clinical features in greater detail.

Results: With a response rate of 78% of Dutch pediatric departments, we identified 89 children, aged 2-18 years, suspected of long-COVID with various complaints. Of these children, 36% experienced severe limitations in daily function. The most common complaints were fatigue, dyspnea, and concentration difficulties with 87%, 55%, and 45% respectively. Our case series emphasizes the nonspecific and broad clinical manifestations seen in post-COVID complaints.

Conclusion: Our study shows that long-COVID is also present in the pediatric population. The main symptoms resemble those previously described in adults. This novel condition demands a multidisciplinary approach with international awareness and consensus to aid early detection and effective management.

Keywords: TB; infections; pneumonia; viral.

MeSH terms

  • Adult
  • COVID-19* / complications
  • Child
  • Dyspnea
  • Fatigue / epidemiology
  • Fatigue / etiology
  • Humans
  • Post-Acute COVID-19 Syndrome
  • SARS-CoV-2