Non-specific symptoms-based pathways for diagnosing less common cancers in primary care: a service evaluation

Br J Gen Pract. 2021 Oct 28;71(712):e846-e853. doi: 10.3399/BJGP.2020.1108. Print 2021 Nov.

Abstract

Background: Although less common cancers account for almost half of all cancer diagnoses in England, their relative scarcity and complex presentation, often with non-specific symptoms, means that patients often experience multiple primary care consultations, long times to diagnosis, and poor clinical outcomes. An urgent referral pathway for non-specific symptoms, the Multidisciplinary Diagnostic Centre (MDC), may address this problem.

Aim: To examine the less common cancers identified during the MDC pilots and consider whether such an approach improves the diagnosis of these cancers.

Design and setting: A service evaluation of five MDC pilot projects in England from December 2016 to March 2019.

Method: Data items were collected by pilot sites in near-real time, based mainly on the English cancer outcomes and services dataset, with additional project-specific items. Simple descriptive and comparative statistics were used, including χ2 tests for proportions and t-tests for means where appropriate.

Results: From 5134 referrals, 378 cancers were diagnosed, of which 218 (58%) were less common. More than 30 different less common tumour types were diagnosed in this cohort. Of the MDC patients with less common cancers, 23% (n = 50) had ≥3 GP consultations before referral and, at programme level, a median time of 57 days was recorded from GP urgent referral to treatment for these tumour types.

Conclusion: A non-specific symptomatic referral route diagnoses a broad range of less common cancers, and can support primary care case management for patients with symptoms of possible cancer that do not qualify for a site-specific urgent referral.

Keywords: Multidisciplinary Diagnostic Centre; less common cancers; neoplasms; non-specific symptoms; primary health care; referral.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cohort Studies
  • England / epidemiology
  • Humans
  • Neoplasms* / diagnosis
  • Primary Health Care
  • Referral and Consultation