A Case of VEXAS Syndrome Complicated by Hemophagocytic Lymphohistiocytosis

J Clin Immunol. 2021 Oct;41(7):1648-1651. doi: 10.1007/s10875-021-01070-y. Epub 2021 Jun 2.

Authors

Alice Grey¹, Pak Leng Cheong², Frederick J Lee³, Edward Abadir⁴, James Favaloro⁴, Shihong Yang⁴, Stephen Adelstein³

Affiliations

¹ Department of Clinical Immunology and Allergy, Royal Prince Alfred Hospital, Sydney, Australia. alice.grey@health.nsw.gov.au.
² Department of Medical Genomics, Royal Prince Alfred Hospital, Sydney, Australia.
³ Department of Clinical Immunology and Allergy, Royal Prince Alfred Hospital, Sydney, Australia.
⁴ Department of Haematology, Royal Prince Alfred Hospital, Sydney, Australia.

PMID: 34080084
DOI: 10.1007/s10875-021-01070-y

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Cytokines / immunology
Genetic Diseases, X-Linked* / genetics
Genetic Diseases, X-Linked* / immunology
Hereditary Autoinflammatory Diseases* / genetics
Hereditary Autoinflammatory Diseases* / immunology
Humans
Lymphohistiocytosis, Hemophagocytic* / genetics
Lymphohistiocytosis, Hemophagocytic* / immunology
Male
Syndrome
Ubiquitin-Activating Enzymes / genetics*

Substances

Cytokines
UBA1 protein, human
Ubiquitin-Activating Enzymes