Effects of Modified Simultaneous Unipolar Saline-Irrigated Radiofrequency Ablation in Patients with Atrial Fibrillation Combined with Mitral Valve Disease

Bo Jiang; Ji-Wei Gu; Yan-Yan Song; Lei Bai; Xu-Dong Liu; Yu-Jing Zhang; Ming-Liang Li; Jian Yang; Li Liu; Yun Wang

doi:10.2147/IJGM.S302209

Effects of Modified Simultaneous Unipolar Saline-Irrigated Radiofrequency Ablation in Patients with Atrial Fibrillation Combined with Mitral Valve Disease

Int J Gen Med. 2021 May 26:14:1547-1553. doi: 10.2147/IJGM.S302209. eCollection 2021.

Authors

Bo Jiang^#¹, Ji-Wei Gu^#¹, Yan-Yan Song¹, Lei Bai¹, Xu-Dong Liu¹, Yu-Jing Zhang¹, Ming-Liang Li¹, Jian Yang¹, Li Liu¹, Yun Wang¹

Affiliation

¹ Department of Cardiovascular Surgery, General Hospital of Ningxia Medical University, Yinchuan, 750004, People's Republic of China.

^# Contributed equally.

Abstract

Objective: To investigate the therapeutic effects of a modified simultaneous unipolar saline-irrigated radiofrequency ablation by intracardiac operation under direct vision in patients with mitral valve diseases combined with atrial fibrillation (AF).

Methods: A total of 168 patients with mitral valve diseases combined with AF who underwent unipolar saline-irrigated radiofrequency ablation modified maze procedures were enrolled and divided into the mitral stenosis (MS) group (n = 87) and the mitral insufficiency (MI) group (n = 81).

Results: Those with a left atrium diameter (LAD) < 55 mm had a better cardioversion effect during the mid-term post-operation than those with a LAD ≥ 55 mm (P < 0.05). The cardioversion effect during the mid-term post-operation was better in those with a duration of AF < 2 years than those with AF ≥ 2 years (P < 0.05). The LAD reduced significantly during the early postoperative period in the MS group (P < 0.05). Compared with the early postoperative period, LAD further reduced, and the EF increased significantly during the mid-term post-operation (P<0.05). The LAD reduced significantly during the early postoperative period in the MI group (P < 0.05), together with relatively decreased EF (P < 0.05). Compared with the early postoperative period, LAD further reduced, and the EF increased significantly during the mid-term post-operation (P<0.05). The improvement of LAD in the MI group during the mid-term post-operation was better than that in the MS group (P < 0.05).

Conclusion: The cardioversion effects and the improvement in cardiac function during the mid-term post-operation were good in the radiofrequency ablation by intracardiac operation under direct vision in patients with different mitral valve diseases combined with AF. The cardioversion effects during the early postoperative period and the mid-term post-operation were better in patients with MI than in those with MS.

Keywords: atrial fibrillation; mitral insufficiency; mitral stenosis; radiofrequency ablation; therapeutic effect.

Grants and funding

This study was funded by the Ningxia Natural Science Foundation Project (No. 2020AAC03367). The funding body had no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.