SCA Medium: A New Culture Medium for the Isolation of All Candida auris Clades

J Fungi (Basel). 2021 May 29;7(6):433. doi: 10.3390/jof7060433.

Abstract

Candida auris is an emerging multidrug-resistant yeast causing nosocomial infections and associated with high mortality in immunocompromised patients. Rapid identification and characterisation are necessary for diagnosis and containing its spread. In this study, we present a selective culture medium for all C. auris clades. This medium is sensitive with a limit of detection ranging between 101 and 102 CFU/mL. The 100% specificity of SCA (specific C. auris) medium is confirmed on a set of 135 Candida strains, 50 bacterial species and 200 human stool samples. Thus, this medium specifically selects for C. auris isolation from clinical samples, allowing the latter to study its phenotypic profile.

Keywords: Candida; Candida auris; culture; emerging fungus; isolation; specific medium.