Mild Symptomatic SARS-CoV-2 P.1 (B.1.1.28) Infection in a Fully Vaccinated 83-Year-Old Man

Marco Fabiani; Katia Margiotti; Antonella Viola; Alvaro Mesoraca; Claudio Giorlandino

doi:10.3390/pathogens10050614

Mild Symptomatic SARS-CoV-2 P.1 (B.1.1.28) Infection in a Fully Vaccinated 83-Year-Old Man

Pathogens. 2021 May 17;10(5):614. doi: 10.3390/pathogens10050614.

Authors

Marco Fabiani¹, Katia Margiotti¹, Antonella Viola¹, Alvaro Mesoraca¹, Claudio Giorlandino^{1

2

3}

Affiliations

¹ Human Genetics Lab, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.
² Department of Biochemistry, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.
³ Department of Prenatal Diagnosis, Fetal-Maternal Medical Centre, ALTAMEDICA, Viale Liegi 45, 00198 Rome, Italy.

Abstract

The novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) and the associated coronavirus disease 2019 (COVID-19) continue to spread throughout the world, causing more than 120 million infections. Several variants of concern (VOCs) have emerged and spread with implications for vaccine efficacy, therapeutic antibody treatments, and possible reinfections. On 17 March 2021, several VOCs were detected, including lineage B.1.1.7, first identified in the UK, B.1.351 in South Africa, Lineage P.1 (B.1.1.28.1) in Brazil, and novel Sub-Lineage A (A.23.1), reported in Uganda, and B.1.525, reported in Nigeria. Here, we describe an 83-year-old man infected with the SARS-CoV-2 P.1 variant after two doses of the BNT162b2 mRNA COVID-19 vaccine.

Keywords: Brazilian variant; COVID-19; P.1 variant; SARS-CoV-2; immunity; vaccine.

Publication types

Case Reports