Clinical Characteristics and Outcomes of COVID-19 in West Virginia

Viruses. 2021 May 5;13(5):835. doi: 10.3390/v13050835.

Abstract

This study examines the clinical characteristics, outcomes and types of management in SARS-CoV-2 infected patients, in the hospitals affiliated with West Virginia University. We included patients from West Virginia with SARS-CoV-2 infection between 15 April to 30 December 2020. Descriptive analysis was performed to summarize the characteristics of patients. Regression analyses were performed to assess the association between baseline characteristics and outcomes. Of 1742 patients, the mean age was 47.5 years (±22.7) and 54% of patients were female. Only 459 patients (26.3%) reported at least one baseline symptom, of which shortness of breath was most common. More than half had at least one comorbidity, with hypertension being the most common. There were 131 severe cases (7.5%), and 84 patients (4.8%) died despite treatment. The mean overall length of hospital stay was 2.6 days (±6.9). Age, male sex, and comorbidities were independent predictors of outcomes. In this study of patients with SARS-CoV-2 infection from West Virginia, older patients with underlying co-morbidities had poor outcomes, and the in-hospital mortality was similar to the national average.

Keywords: COVID-19; SARS-CoV-2; mortality; severity.

MeSH terms

  • Adult
  • Aged
  • COVID-19 / epidemiology*
  • COVID-19 / mortality
  • COVID-19 / therapy*
  • Comorbidity / trends
  • Female
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • SARS-CoV-2 / metabolism
  • SARS-CoV-2 / pathogenicity
  • Treatment Outcome
  • West Virginia / epidemiology