A move in response to starvation

Elife. 2021 Jun 1:10:e69680. doi: 10.7554/eLife.69680.

Abstract

When a yeast cell runs out of fuel, it can increase the flux through a central metabolic pathway by simply changing the location of an enzyme.

Keywords: HMG-CoA Reductase; S. cerevisiae; cell biology; lipid droplet; mevalonate; nucleus-vacuole junction; sterol-ester.

Publication types

  • Comment

MeSH terms

  • Humans
  • Hydroxymethylglutaryl CoA Reductases* / metabolism
  • Metabolic Networks and Pathways
  • Mevalonic Acid
  • Saccharomyces cerevisiae / genetics
  • Saccharomyces cerevisiae / metabolism
  • Starvation*

Substances

  • Hydroxymethylglutaryl CoA Reductases
  • Mevalonic Acid