Acquisition of JAK2 V617F to CALR-mutated clones accelerates disease progression and might enhance growth capacity

Br J Haematol. 2021 Sep;194(5):e89-e92. doi: 10.1111/bjh.17571. Epub 2021 Jun 1.
No abstract available

Keywords: genetic analysis; myelofibrosis; myeloproliferative disease.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Calreticulin / genetics*
  • Disease Progression
  • Female
  • Humans
  • Janus Kinase 2 / genetics*
  • Middle Aged
  • Mutation
  • Myeloproliferative Disorders / genetics*
  • Myeloproliferative Disorders / pathology
  • Thrombocytosis / genetics*
  • Thrombocytosis / pathology

Substances

  • Calreticulin
  • JAK2 protein, human
  • Janus Kinase 2