Pulmonary Mycobacterium abscessus Infection in an 11-Year-Old Child, Successfully Treated with Inhaled/Parenteral Amikacin: A Case Report and Review of Literature

J Trop Pediatr. 2021 May 17;67(2):fmab031. doi: 10.1093/tropej/fmab031.

Abstract

Mycobacterium abscessus appears to be increasing cause of pulmonary infection in children with underlying risk factors including cystic fibrosis, chronic lung disease and immunodeficiency syndromes. We present a case of pulmonary M. abscessus infection in a pediatric patient with primary ciliary dyskinesia and he was successfully treated with parenteral amikacin, linezolid and oral clarithromycin combined with inhaled amikacin. Clinical improvement was observed after adding inhaled amikacin to the treatment.

Keywords: Mycobacterium abscessus; children; infection; inhaled parenteral amikacin.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Amikacin
  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Clarithromycin / therapeutic use
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Mycobacterium Infections, Nontuberculous* / diagnosis
  • Mycobacterium Infections, Nontuberculous* / drug therapy
  • Mycobacterium abscessus*

Substances

  • Anti-Bacterial Agents
  • Amikacin
  • Clarithromycin