In vitro effect of toothpaste with low fluoride combined with sodium trimetaphosphate on dentine erosion

Eur Arch Paediatr Dent. 2021 Oct;22(5):843-849. doi: 10.1007/s40368-021-00636-z. Epub 2021 May 30.

Abstract

Purpose: This study sought to evaluate in vitro the effect of a dentifrice containing sodium trimetaphosphate (TMP) combined or not with low fluoride (500 ppm NaF) on dentine erosion of intrinsic origin.

Methods: Human root dentine blocks were selected based on surface microhardness and randomly allocated into five groups (n = 12): negative control (0 ppm F; no TMP); F500 (500 ppm NaF); F1500 (1500 ppm NaF-positive control); TMP (1% TMP); and F + TMP (500 ppm NaF + 1% TMP). The blocks were submitted to erosion cycles (3 ×/day) for 3 days (0.01 M HCl, pH 1.5-30 s), treatment (1 min-1:3 p/p dentifrice/distilled water) and remineralization (artificial saliva/120 min). Dentine alterations were determined according to the percentage of microhardness loss (%HL), surface loss (SL) and surface analysis by scanning electron microscopy. The data were analyzed using one-way ANOVA (p < 0.05).

Results: The values of SL and %HL in each group were, respectively: negative control (1.36 ± 0.36; 57.29 ± 14.14), F500 (1.46 ± 0.28; 65.66 ± 5.11), F1500 (1.52 ± 0.36; 61.66 ± 5.15), TMP (1.45 ± 0.45; 62.08 ± 3.83) and F + TMP (1.38 ± 0.42; 63.38 ± 6.47). There was no statistically significant difference in all the parameters (p = 0.873 and p = 0.152).

Conclusion: The dentifrices containing TMP combined or not with fluoride were not able to prevent dentine erosion.

Keywords: Dental erosion; Dentine; Fluoride; Prevention and control; Trimetaphosphate.

MeSH terms

  • Cariostatic Agents / pharmacology*
  • Dental Enamel
  • Dentin
  • Fluorides*
  • Hardness
  • Humans
  • Polyphosphates / pharmacology*
  • Random Allocation
  • Sodium Fluoride
  • Tooth Erosion* / prevention & control
  • Toothpastes*

Substances

  • Cariostatic Agents
  • Polyphosphates
  • Toothpastes
  • Sodium Fluoride
  • trimetaphosphoric acid
  • Fluorides