Gastric Cancer Epidemiology

Aaron P Thrift; Theresa H Nguyen

doi:10.1016/j.giec.2021.03.001

Gastric Cancer Epidemiology

Gastrointest Endosc Clin N Am. 2021 Jul;31(3):425-439. doi: 10.1016/j.giec.2021.03.001.

Authors

Aaron P Thrift¹, Theresa H Nguyen²

Affiliations

¹ Section of Epidemiology and Population Sciences, Department of Medicine, Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: aaron.thrift@bcm.edu.
² Baylor Clinic, 6620 Main Street, MS: BCM620, Room 110D, Houston, TX, 77030, USA.

PMID: 34053631
DOI: 10.1016/j.giec.2021.03.001

Abstract

In the United States, the incidence of gastric cancer has decreased over the past five decades. However, despite overall decreasing trends in incidence rates of gastric cancer, rates of noncardia gastric cancer among adults aged less than 50 years in the United States are increasing, and most cases of gastric cancer still present with advanced disease and poor resultant survival. Epidemiologic studies have identified the main risk factors for gastric cancer, including increasing age, male sex, non-White race, Helicobacter pylori infection, and smoking. This article summarizes the current epidemiologic evidence with implications for primary and secondary prevention of gastric cancer.

Keywords: Environment; Genetics; Incidence; Risk factors; Survival.

Publication types

Review

MeSH terms

Adult
Helicobacter Infections* / complications
Helicobacter Infections* / epidemiology
Helicobacter pylori*
Humans
Incidence
Male
Risk Factors
Stomach Neoplasms* / epidemiology
United States / epidemiology