Intraoperative management of thrombectomy for acute ischemic stroke: Do we need general anesthesia?

Best Pract Res Clin Anaesthesiol. 2021 Jul;35(2):171-179. doi: 10.1016/j.bpa.2020.10.003. Epub 2020 Oct 16.

Abstract

Since 2015, endovascular thrombectomy has been established as the standard of care for re-establishing cerebral blood flow in patients with acute ischemic stroke. Several retrospective observational studies and prospective clinical trials have investigated two anesthetic techniques for endovascular stroke therapy: general anesthesia (GA) and conscious sedation (CS). The recent randomized studies suggest that GA is associated with higher rates of successful recanalization and better functional independence at 3 months compared with the CS technique. However, CS techniques are highly variable, and there is currently a lack of consensus on which anesthetic approach is best in all patients. Numerous patient and procedural factors should ultimately guide the decision of whether GA or CS should be used for a particular patient.

Keywords: acute ischemic stroke; anesthesia management; endovascular stroke therapy.

Publication types

  • Review

MeSH terms

  • Anesthesia, General / adverse effects
  • Anesthesia, General / methods*
  • Brain Ischemia / diagnosis
  • Brain Ischemia / physiopathology
  • Brain Ischemia / surgery*
  • Conscious Sedation / adverse effects
  • Conscious Sedation / methods*
  • Humans
  • Intraoperative Care / methods*
  • Ischemic Stroke / diagnosis
  • Ischemic Stroke / physiopathology
  • Ischemic Stroke / surgery*
  • Prospective Studies
  • Retrospective Studies
  • Thrombectomy / methods*