Discovery of G6PD deficiency in a patient with DUSP22-rearranged ALK-negative anaplastic large cell lymphoma in leukemic phase

Int J Lab Hematol. 2022 Feb;44(1):67-68. doi: 10.1111/ijlh.13583. Epub 2021 May 21.

Authors

Jessica Anderson¹, Eileen Putnam², Wei Liu², Madhu P Menon³

Affiliations

¹ School of Medicine, Wayne State University, Detroit, MI, USA.
² Department of Pathology and Laboratory Medicine, Henry Ford Hospital, Detroit, MI, USA.
³ Department of Pathology, University of Utah and ARUP Laboratories, Salt Lake City, UT, USA.

PMID: 34019742
DOI: 10.1111/ijlh.13583

No abstract available

Keywords: ALK-negative ALCL; DUSP22; G6PD deficiency; blister cells; doughnut cells; rasburicase.

Publication types

Case Reports

MeSH terms

Aged, 80 and over
Anaplastic Lymphoma Kinase* / genetics
Anaplastic Lymphoma Kinase* / metabolism
Dual-Specificity Phosphatases* / genetics
Dual-Specificity Phosphatases* / metabolism
Glucosephosphate Dehydrogenase Deficiency* / enzymology
Glucosephosphate Dehydrogenase Deficiency* / genetics
Glucosephosphate Dehydrogenase Deficiency* / pathology
Humans
Lymphoma, Large-Cell, Anaplastic* / enzymology
Lymphoma, Large-Cell, Anaplastic* / genetics
Lymphoma, Large-Cell, Anaplastic* / pathology
Male
Mitogen-Activated Protein Kinase Phosphatases* / genetics
Mitogen-Activated Protein Kinase Phosphatases* / metabolism
Neoplasm Proteins* / genetics
Neoplasm Proteins* / metabolism

Substances

Neoplasm Proteins
ALK protein, human
Anaplastic Lymphoma Kinase
Mitogen-Activated Protein Kinase Phosphatases
DUSP22 protein, human
Dual-Specificity Phosphatases