Method of Measuring High-LET Particles Dose

Maya Dymova; Maria Dmitrieva; Elena Kuligina; Vladimir Richter; Sergey Savinov; Ivan Shchudlo; Tatiana Sycheva; Iuliia Taskaeva; Sergey Taskaev

doi:10.1667/RADE-21-00015.1

Method of Measuring High-LET Particles Dose

Radiat Res. 2021 Aug 1;196(2):192-196. doi: 10.1667/RADE-21-00015.1.

Authors

Affiliations

¹ Institute of Chemical Biology and Fundamental Medicine, iberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
² Budker Institute of Nuclear Physics, iberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
³ Research Institute of Clinical and Experimental Lymphology - Branch of the Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
⁴ Novosibirsk State University, Novosibirsk, Russia.

PMID: 34019668
DOI: 10.1667/RADE-21-00015.1

Abstract

In boron neutron capture therapy, the total absorbed dose is the sum of four dose components with different relative biological effectiveness (RBE): boron dose, "nitrogen" dose, fast neutron dose and γ-ray dose. We present a new approach for measuring the first three doses. In this work, we provide the details of this method of dose measurement and results when this proposed method is employed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Boron Neutron Capture Therapy / methods*
Fast Neutrons / therapeutic use
Gamma Rays
Humans
Radiation Dosage*
Radiotherapy Dosage / standards
Relative Biological Effectiveness