Fc-fused IL-7 mobilizes long-term HSCs in a pro-B cell-dependent manner and synergizes with G-CSF and AMD3100

Leukemia. 2021 Oct;35(10):3030-3034. doi: 10.1038/s41375-021-01274-6. Epub 2021 May 18.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-HIV Agents / pharmacology
  • Benzylamines / pharmacology*
  • Cyclams / pharmacology*
  • Granulocyte Colony-Stimulating Factor / pharmacology*
  • Hematopoietic Stem Cell Mobilization / methods*
  • Hematopoietic Stem Cells / cytology
  • Hematopoietic Stem Cells / drug effects
  • Hematopoietic Stem Cells / physiology*
  • Immunoglobulin Fc Fragments / metabolism*
  • Interleukin-7 / metabolism*
  • Mice
  • Precursor Cells, B-Lymphoid / cytology*
  • Precursor Cells, B-Lymphoid / drug effects
  • Precursor Cells, B-Lymphoid / metabolism

Substances

  • Anti-HIV Agents
  • Benzylamines
  • Cyclams
  • Immunoglobulin Fc Fragments
  • Interleukin-7
  • Granulocyte Colony-Stimulating Factor
  • plerixafor