Supplementation-based hypoglycemia guidelines including donor breast milk reduce NICU admission

J Perinatol. 2021 Aug;41(8):2088-2094. doi: 10.1038/s41372-021-01069-8. Epub 2021 May 18.

Abstract

Objective: To study the effects of a supplementation-based hypoglycemia guideline including donor (DM) on NICU admission, exclusive breastfeeding, and blood glucose concentrations in infants at-risk for neonatal hypoglycemia (NH).

Project design: We integrated DM, feeding supplementation, and reduced frequency of blood glucose testing into an NH bundle for term and late-preterm newborns. We then examined NICU admission rates and rates of exclusive breastfeeding at discharge.

Results: NICU admission rates were reduced to 6% (-10%). Exclusive breastfeeding rates increased to 55% (+22%). Median cost of DM utilization was $13.73 per patient with an average volume of 50.8 ml/infant. DM supplementation resulted in similar times to last hypoglycemic episode and greater increases in blood glucose compared to expressed breast milk or breastfeeding alone (+9.6 mg/dL, p < 0.05).

Conclusions: A supplementation-based hypoglycemia guideline including donor milk may be an effective way to reduce NICU admissions for asymptomatic hypoglycemia and support mothers in achieving breastfeeding goals.

MeSH terms

  • Breast Feeding
  • Dietary Supplements
  • Female
  • Humans
  • Hypoglycemia* / epidemiology
  • Hypoglycemia* / prevention & control
  • Infant
  • Infant, Newborn
  • Intensive Care Units, Neonatal
  • Milk, Human*