SF3B1 as therapeutic target in FLT3/ITD positive acute myeloid leukemia

Leukemia. 2021 Sep;35(9):2698-2702. doi: 10.1038/s41375-021-01273-7. Epub 2021 May 17.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alternative Splicing*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Biomarkers, Tumor / genetics
  • Cell Proliferation
  • Humans
  • Leukemia, Myeloid, Acute / drug therapy
  • Leukemia, Myeloid, Acute / genetics
  • Leukemia, Myeloid, Acute / pathology*
  • Mutation*
  • Phosphoproteins / genetics*
  • Prognosis
  • RNA Splicing Factors / genetics*
  • Tandem Repeat Sequences*
  • Tumor Cells, Cultured
  • fms-Like Tyrosine Kinase 3 / genetics*

Substances

  • Biomarkers, Tumor
  • Phosphoproteins
  • RNA Splicing Factors
  • SF3B1 protein, human
  • FLT3 protein, human
  • fms-Like Tyrosine Kinase 3