Predictive and diagnosis models of stroke from hemodynamic signal monitoring

Med Biol Eng Comput. 2021 Jun;59(6):1325-1337. doi: 10.1007/s11517-021-02354-6. Epub 2021 May 14.

Abstract

This work presents a novel and promising approach to the clinical management of acute stroke. Using machine learning techniques, our research has succeeded in developing accurate diagnosis and prediction real-time models from hemodynamic data. These models are able to diagnose stroke subtype with 30 min of monitoring, to predict the exitus during the first 3 h of monitoring, and to predict the stroke recurrence in just 15 min of monitoring. Patients with difficult access to a CT scan and all patients that arrive at the stroke unit of a specialized hospital will benefit from these positive results. The results obtained from the real-time developed models are the following: stroke diagnosis around 98% precision (97.8% sensitivity, 99.5% specificity), exitus prediction with 99.8% precision (99.8% Sens., 99.9% Spec.), and 98% precision predicting stroke recurrence (98% Sens., 99% Spec.). Graphical abstract depicting the complete process since a patient is monitored until the data collected is used to generate models.

Keywords: Exitus forecasting; Hemodynamic monitoring; Rebleeding prediction; Stroke diagnosis; Supervised machine learning; Time series.

MeSH terms

  • Humans
  • Machine Learning
  • Stroke* / diagnosis
  • Tomography, X-Ray Computed