(Chemo)Radiotherapy-Immunotherapy Combinations: Time to Get Tailored?

Clin Cancer Res. 2021 Jul 15;27(14):3815-3817. doi: 10.1158/1078-0432.CCR-21-1173. Epub 2021 May 13.

Abstract

Chemoradiotherapy is considered an immunogenic anticancer treatment. Data obtained during the course of chemoradiotherapy treatment of patients with cervical cancer show heterogeneous changes in the tumor immune landscape, highlighting the need for patient selection to rationally design successful combined immunotherapies. Blood-based biomarkers could be valuable to perform such stratification.See related article by Chen et al., p. 3990.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Chemoradiotherapy
  • Drug Therapy, Combination
  • Female
  • Humans
  • Immunologic Factors
  • Immunotherapy*
  • Uterine Cervical Neoplasms*

Substances

  • Immunologic Factors