Restless Sleep Disorder

Lourdes M DelRosso; Rosalia Silvestri; Raffaele Ferri

doi:10.1016/j.jsmc.2021.03.003

Restless Sleep Disorder

Sleep Med Clin. 2021 Jun;16(2):381-387. doi: 10.1016/j.jsmc.2021.03.003.

Authors

Lourdes M DelRosso¹, Rosalia Silvestri², Raffaele Ferri³

Affiliations

¹ University of Washington, Seattle Washington, Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA 98105, USA. Electronic address: Lourdesdelrosso@me.com.
² Sleep Medicine Center, Department of Clinical and Experimental Medicine, University of A.O.U.G. Martino - Pad. H, 1o piano, Via Consolare Valeria, 1, 98125 Messina (ME), Italy.
³ Oasi Research Institute - IRCCS, Via C Ruggero 73, 94018 Troina, Italy.

PMID: 33985662
DOI: 10.1016/j.jsmc.2021.03.003

Abstract

Restless sleep disorder is (RSD) a condition characterized by frequent large movements during sleep associated with daytime impairment. RSD has been studied in children aged 6 to 18 years. Polysomnography is necessary for the diagnosis of RSD. The current diagnostic criteria include more than 5 large movements per hour of sleep documented by PSG. The pathophysiology is not known yet, but iron deficiency and sleep instability and increased sympathetic activation are suspected to play a role. Iron supplementation is the only treatment option studied so far.

Keywords: Children; Restless sleep; Restless sleep disorder.

Publication types

Review

MeSH terms

Humans
Parasomnias* / diagnosis
Parasomnias* / physiopathology
Parasomnias* / therapy
Polysomnography