Towards improved breast mass detection using dual-view mammogram matching

Med Image Anal. 2021 Jul:71:102083. doi: 10.1016/j.media.2021.102083. Epub 2021 Apr 22.

Abstract

Breast cancer screening benefits from the visual analysis of multiple views of routine mammograms. As for clinical practice, computer-aided diagnosis (CAD) systems could be enhanced by integrating multi-view information. In this work, we propose a new multi-tasking framework that combines craniocaudal (CC) and mediolateral-oblique (MLO) mammograms for automatic breast mass detection. Rather than addressing mass recognition only, we exploit multi-tasking properties of deep networks to jointly learn mass matching and classification, towards better detection performance. Specifically, we propose a unified Siamese network that combines patch-level mass/non-mass classification and dual-view mass matching to take full advantage of multi-view information. This model is exploited in a full image detection pipeline based on You-Only-Look-Once (YOLO) region proposals. We carry out exhaustive experiments to highlight the contribution of dual-view matching for both patch-level classification and examination-level detection scenarios. Results demonstrate that mass matching highly improves the full-pipeline detection performance by outperforming conventional single-task schemes with 94.78% as Area Under the Curve (AUC) score and a classification accuracy of 0.8791. Interestingly, mass classification also improves the performance of mass matching, which proves the complementarity of both tasks. Our method further guides clinicians by providing accurate dual-view mass correspondences, which suggests that it could act as a relevant second opinion for mammogram interpretation and breast cancer diagnosis.

Keywords: Breast cancer; Computer-aided diagnosis; Dual-view matching; Information fusion; Mass detection; Siamese networks.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Breast / diagnostic imaging
  • Breast Neoplasms* / diagnostic imaging
  • Diagnosis, Computer-Assisted
  • Early Detection of Cancer
  • Female
  • Humans
  • Mammography*
  • Radiographic Image Interpretation, Computer-Assisted