A voltammetric sensor based on mixed proton-electron conducting composite including metal-organic framework JUK-2 for determination of citalopram

Maria Madej; Dariusz Matoga; Klaudia Skaźnik; Radosław Porada; Bogusław Baś; Jolanta Kochana

doi:10.1007/s00604-021-04835-9

A voltammetric sensor based on mixed proton-electron conducting composite including metal-organic framework JUK-2 for determination of citalopram

Mikrochim Acta. 2021 May 11;188(6):184. doi: 10.1007/s00604-021-04835-9.

Authors

Maria Madej¹, Dariusz Matoga², Klaudia Skaźnik³, Radosław Porada⁴, Bogusław Baś⁴, Jolanta Kochana³

Affiliations

¹ Faculty of Chemistry, Department of Analytical Chemistry, Jagiellonian University, Gronostajowa 2, 30-387, Kraków, Poland. marysia.madej@doctoral.uj.edu.pl.
² Faculty of Chemistry, Department of Inorganic Chemistry, Jagiellonian University, Gronostajowa 2, 30-387, Kraków, Poland.
³ Faculty of Chemistry, Department of Analytical Chemistry, Jagiellonian University, Gronostajowa 2, 30-387, Kraków, Poland.
⁴ Faculty of Materials and Ceramics, Department of Analytical Chemistry, AGH University of Science and Technology, A. Mickiewicza 30, 30-059, Kraków, Poland.

Abstract

A voltammetric sensor has been developed based on glassy carbon electrode (GCE) modification with nanocomposite consisting of manganese-based metal-organic framework (JUK-2), multi-walled carbon nanotubes (MWCNTs), and gold nanoparticles (AuNPs) for detection of citalopram (CIT). The composition and morphology of JUK-2-MWCNTs-AuNPs/GCE were characterized by X-ray powder diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), energy dispersion spectroscopy (EDS), and scanning electron microscopy (SEM). The electrochemical properties investigated using electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) indicated that the fabricated hybrid material exhibits the properties of mixed ion-electron conductor (MIEC). Using staircase voltammetry (SCV), under optimized conditions, the fabricated sensor shows a linear response in three CIT concentration ranges, 0.05-1.0, 1.0-10.0 and 15.0-115.0 μmol L^-1, with a detection limit of 0.011 μmol L^-1. The JUK-2-MWCNTs-AuNPs/GCE was successfully employed for the determination of CIT in pharmaceutical, environmental waters, and biological samples with satisfactory recoveries (98.6-104.8%).

Keywords: Citalopram; Electrochemical sensor; Gold nanoparticles; Metal-organic framework; Mixed ion-electron conductor; Multi-walled carbon nanotubes.

Publication types

Research Support, Non-U.S. Gov't

Abstract

Publication types

Grants and funding