Discovery and application of dietary compounds to optimize human health, a focus on skeletal muscle regeneration

Abstract

Worldwide, the number of persons over the age of 65 years and those at risk of malnutrition (over and under) is growing, and the prevalence of diet-related chronic disease is at a record high. Pathologies that are linked to poor nutrition underlie the leading causes of death. Safe and effective strategies to improve human health outcomes are urgently required. Identification of nutrient needs for health outcomes has led to the development of food products, supplements, and dietary pattern recommendations. Application of these nutrient-based therapies have the potential to optimize clinical outcomes, such as tissue regeneration post-skeletal muscle trauma. However, despite progress in identifying nutrient needs there is often a delay in the utilization of products in clinical practice.