GSpace: an exact coalescence simulator of recombining genomes under isolation by distance

Bioinformatics. 2021 Oct 25;37(20):3673-3675. doi: 10.1093/bioinformatics/btab261.

Abstract

Motivation: Simulation-based inference can bypass the limitations of statistical methods based on analytical approximations, but software allowing simulation of structured population genetic data without the classical n-coalescent approximations (such as those following from assuming large population size) are scarce or slow.

Results: We present GSpace, a simulator for genomic data, based on a generation-by-generation coalescence algorithm taking into account small population size, recombination and isolation by distance.

Availability and implementation: Freely available at site web INRAe (http://www1.montpellier.inra.fr/CBGP/software/gspace/download.html).