Abstract
This cohort study examines the association of BRCA1 and BRCA2 with tumor mutation burden and response to immune checkpoint inhibitors.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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BRCA1 Protein / genetics*
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BRCA2 Protein / genetics*
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Biomarkers, Tumor / genetics
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Breast Neoplasms / drug therapy*
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Breast Neoplasms / genetics*
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Breast Neoplasms / mortality
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Cohort Studies
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Female
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Humans
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Immune Checkpoint Inhibitors / therapeutic use*
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Kaplan-Meier Estimate
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Mutation
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Tumor Burden
Substances
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BRCA1 Protein
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BRCA1 protein, human
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BRCA2 Protein
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BRCA2 protein, human
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Biomarkers, Tumor
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Immune Checkpoint Inhibitors