Orthobiologics in the treatment of hip disorders

World J Stem Cells. 2021 Apr 26;13(4):304-316. doi: 10.4252/wjsc.v13.i4.304.

Abstract

Orthobiologics are biological materials that are intended for the regeneration or healing of bone, cartilage and soft tissues. In this review we discuss the use of orthobiologics for hip disorders providing an update. The orthobiologics included in this article are hyaluronic acid, platelet rich plasma, bone marrow, adipose tissue and expanded mesenchymal stem cells. We explain the concepts and definitions of each orthobiological product, and the literature regarding its use in the hip joint. The paucity of guidelines for the production and characterization of the biological products leads to uneven results across the literature. Each biologic therapy has indications and benefits; however, noteworthy are the characterization of the orthobiologics, the application method and outcome analysis for further improvement of each technique.

Keywords: Adipose tissue; Bone marrow; Hip disorders; Mesenchymal stem cells; Orthobiologics; Platelet-rich plasma.

Publication types

  • Review