COVID-19 influences lung microbiota dynamics and favors the emergence of rare infectious diseases: A case report of Hafnia Alvei pneumonia

J Crit Care. 2021 Aug:64:173-175. doi: 10.1016/j.jcrc.2021.04.008. Epub 2021 Apr 18.

Abstract

The coronavirus disease 2019 causes a wide degree of organ dysfunction and is associated with bacterial secondary infections. We reported lung microbiota dynamics in a critically ill patient with coronavirus disease 2019, who developed severe Hafnia alvei ventilator-associated pneumonia and required extracorporeal membrane oxygenation support.

Keywords: ARDS; COVID-19; Critical care; Hafnia Alvei; Pneumonia; Sepsis.

Publication types

  • Case Reports

MeSH terms

  • Bronchoalveolar Lavage
  • COVID-19 / complications*
  • COVID-19 / microbiology
  • Dysbiosis
  • Enterobacteriaceae Infections / diagnosis*
  • Enterobacteriaceae Infections / drug therapy
  • Hafnia alvei / isolation & purification*
  • Humans
  • Lung / microbiology*
  • Male
  • Meropenem / therapeutic use
  • Microbiota*
  • Middle Aged
  • Pneumonia, Ventilator-Associated / diagnosis*
  • Pneumonia, Ventilator-Associated / drug therapy
  • Respiration, Artificial / adverse effects
  • Respiratory Distress Syndrome / etiology*
  • Respiratory Distress Syndrome / microbiology
  • SARS-CoV-2

Substances

  • Meropenem