Magnetic shielding of parahydrogen hyperpolarization experiments for the masses

Magn Reson Chem. 2021 Dec;59(12):1180-1186. doi: 10.1002/mrc.5167. Epub 2021 May 18.

Abstract

We report on the inexpensive ($80) custom electronics for efficient robust and fast degaussing of mu-metal shields for use in parahydrogen induced polarization experiments. The degaussing process is fully automated and can be performed in ~2 seconds resulting in residual magnetic field of <20 nT. The utility of this device is demonstrated for 15N hyperpolarization of [15N3]metronidazole below 1 microtesla. The reported electronics will be of practical use to those working in the field of parahydrogen utilizing both hydrogenative approaches for magnetic field cycling and non-hydrogenative approaches employing sub-microtesla magnetic fields to create level anti-crossing for polarization transfer from parahydrogen-derived nascent protons to the heteronucleus.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Hydrogen
  • Magnetic Phenomena*
  • Magnetic Resonance Imaging*
  • Magnetic Resonance Spectroscopy

Substances

  • Hydrogen