Nanoceutical Adjuvants as Wound Healing Material: Precepts and Prospects

Int J Mol Sci. 2021 Apr 29;22(9):4748. doi: 10.3390/ijms22094748.

Abstract

Dermal wound healing describes the progressive repair and recalcitrant mechanism of 12 damaged skin, and eventually, reformatting and reshaping the skin. Many probiotics, nutritional supplements, metal nanoparticles, composites, skin constructs, polymers, and so forth have been associated with the improved healing process of wounds. The exact mechanism of material-cellular interaction is a point of immense importance, particularly in pathological conditions such as diabetes. Bioengineered alternative agents will likely continue to dominate the outpatient and perioperative management of chronic, recalcitrant wounds as new products continue to cut costs and improve the wound healing process. This review article provides an update on the various remedies with confirmed wound healing activities of metal-based nanoceutical adjuvanted agents and also other nano-based counterparts from previous experiments conducted by various researchers.

Keywords: bioengineered alternatives; dermal wound healing; metal nanoparticles; nanoceuticals.

Publication types

  • Review

MeSH terms

  • Adjuvants, Pharmaceutic / therapeutic use*
  • Anti-Infective Agents, Local / therapeutic use
  • Bandages
  • Biocompatible Materials
  • Humans
  • Hydrogels
  • Nanomedicine / trends*
  • Nanoparticles / therapeutic use*
  • Neovascularization, Physiologic
  • Phytotherapy
  • Re-Epithelialization
  • Regeneration
  • Skin / immunology
  • Skin / injuries
  • Skin / pathology
  • Skin Physiological Phenomena
  • Skin Transplantation
  • Wound Closure Techniques
  • Wound Healing / drug effects*
  • Wound Infection / prevention & control

Substances

  • Adjuvants, Pharmaceutic
  • Anti-Infective Agents, Local
  • Biocompatible Materials
  • Hydrogels