Letter to the Editor: Is there an Indication for Testing the Methylenetetrahydrofolate reductase A1298C Variant in Routine Clinical Settings?

Ann Clin Lab Sci. 2021 Mar;51(2):277-279.

Gustavo Cernera^{1

2}, Alessandro Di Minno^{2

3}, Ausilia Elce^{2

4}, Renato Liguori^{2

5}, Dario Bruzzese⁶, Antonella Miriam Di Lullo⁷, Giuseppe Castaldo^{1

2}, Felice Amato^{1

2}, Federica Zarrilli^{8

2}, Marika Comegna^{1

2}

¹ Department of Molecular Medicine and Medical Biotechnologies, University of Naples "Federico II".
² CEINGE - Advanced Biotechnologies.
³ Department of Pharmacy, University of Naples "Federico II".
⁴ Telematic University "Pegaso".
⁵ Department of Sciences and Technologies, University of Naples "Parthenope".
⁶ Department of Public Health, University of Naples "Federico II", and Department of Neuroscience, Reproductive and Odontostomatologic Sciences, University of Naples "Federico II,"Naples, Italy.
⁷ Department of Neuroscience, Reproductive and Odontostomatologic Sciences, University of Naples "Federico II,"Naples, Italy.
⁸ Department of Molecular Medicine and Medical Biotechnologies, University of Naples "Federico II" federica.zarrilli@unina.it.

No abstract available

Keywords: Genetic predisposition; Homocysteine; Hyperhomocysteine; MTHFR; Mutations; RealTime PCR.

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