One new cis p-coumaroyl copaborneol-type sesquiterpenoid (1), together with its known trans isomer (2) and six other known p-coumaroyl humulane-type sesquiterpenoids (3-8), were isolated from the whole plants of Pilea cavaleriei. Their structures were determined by spectroscopic data. Compounds 1-4 exhibited moderate antimycobacterial activity against Mycobacterium tuberculosis H37Rv.
Keywords: Pilea cavaleriei; Urticaceae; antimycobacterial activity; sesquiterpenoids.