Alpha-1 Antitrypsin Deficiency: Home Therapy

Front Pharmacol. 2021 Apr 15:12:575402. doi: 10.3389/fphar.2021.575402. eCollection 2021.

Abstract

While available in only a few countries, home therapy is a possible strategy for the treatment of alpha-1 antitrypsin deficiency. We want to describe our experience in the management of human alpha-1 antitrypsin using home care intravenous augmentation therapy during this emergency period caused by SARS-CoV2 infection. We assessed the safety of the home treatment and the quality of life of patients enrolled in the program.

Keywords: CoV-2; QOL score; SARS; alpha-1 antitrypsin (A1AT); augmentation therapy; home therapy.