Relationship Between Helicobacter pylori Infection and Arteriosclerosis

Yoshitaka Furuto; Mariko Kawamura; Jumpei Yamashita; Takahiro Yoshikawa; Akio Namikawa; Rei Isshiki; Hiroko Takahashi; Yuko Shibuya

doi:10.2147/IJGM.S303071

Relationship Between Helicobacter pylori Infection and Arteriosclerosis

Int J Gen Med. 2021 Apr 23:14:1533-1540. doi: 10.2147/IJGM.S303071. eCollection 2021.

Authors

Yoshitaka Furuto¹, Mariko Kawamura¹, Jumpei Yamashita¹, Takahiro Yoshikawa¹, Akio Namikawa¹, Rei Isshiki¹, Hiroko Takahashi¹, Yuko Shibuya¹

Affiliation

¹ Department of Hypertension and Nephrology, NTT Medical Centre, Tokyo, Japan.

Abstract

It is reported that Helicobacter pylori (H. pylori) infection may be linked to non-digestive tract diseases, such as arteriosclerosis including dyslipidemia, diabetes, obesity, hypertension, and cardiovascular disease. Therefore, we reviewed recent studies available in PubMed dealing with the mechanisms of arteriosclerosis due to H. pylori infection and the effects of H. pylori eradication. Conventional studies suggested that H. pylori infection may increase the risk of arteriosclerosis. A large interventional study is required to clarify the causal relationships and the effects of bacterial eradication.

Keywords: Helicobacter pylori infection; arteriosclerosis; hypertension.

Publication types

Review

Grants and funding

This work was not supported by any funding.