Trends in the proportion of resistant bacteria involved in ventilator-associated pneumonia as the first hospital-acquired infection in intensive care units between 2003 and 2016 in Lyon, France

Jordan Teoli; Sélilah Amour; Cédric Dananché; Olivier Dauwalder; Solweig Gerbier-Colomban; Catherine-Cécile Mauranne; Violette Zorio; Céline Monard; Sophie Arnal; Arnaud Friggeri; Alain Lepape; Claude Guerin; Thomas Rimmelé; Laurent Argaud; Elodie Munier-Marion; Marie-Paule Gustin; Philippe Vanhems

doi:10.1016/j.ajic.2021.04.078

Trends in the proportion of resistant bacteria involved in ventilator-associated pneumonia as the first hospital-acquired infection in intensive care units between 2003 and 2016 in Lyon, France

Am J Infect Control. 2021 Nov;49(11):1454-1456. doi: 10.1016/j.ajic.2021.04.078. Epub 2021 Apr 27.

Authors

Jordan Teoli¹, Sélilah Amour¹, Cédric Dananché², Olivier Dauwalder³, Solweig Gerbier-Colomban¹, Catherine-Cécile Mauranne¹, Violette Zorio⁴, Céline Monard⁴, Sophie Arnal⁴, Arnaud Friggeri⁵, Alain Lepape⁵, Claude Guerin⁴, Thomas Rimmelé⁴, Laurent Argaud⁴, Elodie Munier-Marion¹, Marie-Paule Gustin⁶, Philippe Vanhems²

Affiliations

¹ Service d'Hygiène, Epidémiologie, Infectiovigilance et Prévention, Hospices Civils de Lyon, Lyon, France.
² Service d'Hygiène, Epidémiologie, Infectiovigilance et Prévention, Hospices Civils de Lyon, Lyon, France; Laboratoire des Pathogènes Emergents, Fondation Mérieux, Centre International de Recherche en Infectiologie (CIRI), INSERM U1111, CNRS, UMR5308, ENS de Lyon, UCBL1, Lyon, France.
³ Institut des agents infectieux, Groupement Hospitalier Nord, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
⁴ Services de Réanimation, Hospices Civils de Lyon, Lyon, France.
⁵ Laboratoire des Pathogènes Emergents, Fondation Mérieux, Centre International de Recherche en Infectiologie (CIRI), INSERM U1111, CNRS, UMR5308, ENS de Lyon, UCBL1, Lyon, France; Services de Réanimation, Hospices Civils de Lyon, Lyon, France.
⁶ Laboratoire des Pathogènes Emergents, Fondation Mérieux, Centre International de Recherche en Infectiologie (CIRI), INSERM U1111, CNRS, UMR5308, ENS de Lyon, UCBL1, Lyon, France.

PMID: 33930517
DOI: 10.1016/j.ajic.2021.04.078

Abstract

The aim of this study was to describe the proportion of multidrug-resistant microorganisms (MDROs) involved in ventilator-associated pneumonia (VAP) as the first hospital-acquired infection in 536 adults with restricted risk factors for MDRO-related infection. We found a significant decrease in the percentage of MDROs involved in VAP between 2003 and 2016 and this percentage increased when VAP occurred after day 10.

Keywords: Intensive care unit; Multidrug resistant bacteria.

MeSH terms

Adult
Bacteria
Cross Infection* / epidemiology
Hospitals
Humans
Intensive Care Units
Pneumonia, Ventilator-Associated* / epidemiology