How to Manage a Patient with Haemophilia and ACS Requiring PCI: A Battle between Bleeding and Thrombosis

Konstantinos C Theodoropoulos; Sofia Vakalopoulou; Maria Oikonomou; George Stavropoulos; Antonios Ziakas; Ioannis Kanonidis; George Kassimis

doi:10.3390/medicina57040352

How to Manage a Patient with Haemophilia and ACS Requiring PCI: A Battle between Bleeding and Thrombosis

Medicina (Kaunas). 2021 Apr 7;57(4):352. doi: 10.3390/medicina57040352.

Authors

Konstantinos C Theodoropoulos^{1

2}, Sofia Vakalopoulou³, Maria Oikonomou¹, George Stavropoulos¹, Antonios Ziakas², Ioannis Kanonidis¹, George Kassimis¹

Affiliations

¹ Second Cardiology Department, Hippokration Hospital, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece.
² First Cardiology Department, University General Hospital AHEPA, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece.
³ Haemophilia Centre of Northern Greece, Second Propaedeutic Department of Internal Medicine, Medical School, Hippokration Hospital, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece.

Abstract

We present the case of a 70-year-old man with a history of haemophilia B, who presented to our hospital with a non-ST-elevation myocardial infarction. The patient, following consultation by a haemophilia expert, was revascularized with percutaneous coronary intervention (PCI) under adequate clotting factor administration. Patients with haemophilia and acute coronary syndrome, are susceptible to periprocedural bleeding and thrombotic events during PCI, and therefore a balanced management plan should always be implemented by a multidisciplinary team.

Keywords: Haemophilia B; NSTE-ACS; PCI; bleeding; coagulation factors; factor IX; thrombosis.

Publication types

Case Reports

MeSH terms

Acute Coronary Syndrome* / complications
Acute Coronary Syndrome* / therapy
Aged
Hemophilia A* / complications
Hemophilia A* / drug therapy
Humans
Male
Non-ST Elevated Myocardial Infarction*
Percutaneous Coronary Intervention*
Thrombosis*
Treatment Outcome