Personalized, Predictive, Participatory, Precision, and Preventive (P5) Medicine in Rotator Cuff Tears

Umile Giuseppe Longo; Arianna Carnevale; Carlo Massaroni; Daniela Lo Presti; Alessandra Berton; Vincenzo Candela; Emiliano Schena; Vincenzo Denaro

doi:10.3390/jpm11040255

Personalized, Predictive, Participatory, Precision, and Preventive (P5) Medicine in Rotator Cuff Tears

J Pers Med. 2021 Apr 1;11(4):255. doi: 10.3390/jpm11040255.

Authors

Umile Giuseppe Longo¹, Arianna Carnevale^{1

2}, Carlo Massaroni², Daniela Lo Presti², Alessandra Berton¹, Vincenzo Candela¹, Emiliano Schena², Vincenzo Denaro¹

Affiliations

¹ Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via Álvaro del Portillo, 00128 Rome, Italy.
² Unit of Measurements and Biomedical Instrumentation, Campus Bio-Medico University, Via Álvaro del Portillo, 00128 Rome, Italy.

Abstract

Rotator cuff (RC) disease is a common musculoskeletal disorder of the shoulder entailing pain, with reduced functionality and quality of life. The main objective of this study was to present a perspective of the current scientific evidence about personalized, predictive, participatory, precision, and preventive approaches in the management of RC diseases. The personalized, predictive, participatory, precision and preventive (P5) medicine model is an interdisciplinary and multidisciplinary approach that will provide researchers and clinicians with a comprehensive patrimony of knowledge in the management of RC diseases. The ability to define genetic predispositions in conjunction with the evaluation of lifestyle and environmental factors may boost the tailoring of diagnosis and therapy in patients suffering from RC diseases.

Keywords: orthopedics; participatory medicine; personalized medicine; precision medicine; predictive medicine; preventive medicine; rehabilitation; rotator cuff.