To explore the focus and trends in real-world studies in Chinese through knowledge mapping method, databases CNKI, VIP, Wanfang and Sinomed were retrieved, with 1 757 relevant articles published before September 30rd, 2020 finally included, whose bibliographical records were imported into NoteExpress to avoid duplication and check relativity. VOSviewer, a bibliometric analysis tool, was used to analyze their development. It was found that real-world studies have mainly taken shape after 2010, in which traditional Chinese medicine research plays an important role. China Journal of Chinese Material Medica was the leading journal with 120 papers, the China Academy of Chinese Medical Sciences the most contribution institution with 338 papers, and Xie Yanming from the institution the most contribution author with 250 papers. This study helps clinicians and researchers in better understanding the evolution of real-world research over more than two decades in China.
文章通过回顾性可视化分析方法，探讨有关真实世界研究中文文献的热点与趋势。本文检索了知网、维普、万方及中国生物医学文献数据库，文献收录时间从数据库起始截至 2020 年 9 月 30 日。将检索到的文献导入 NoteExpress 后做去重及筛查，最终纳入 1 757 篇文献，并利用 VOSviewer 软件做文献计量学分析。发现真实世界国内文献研究主要在 2010 年后形成一定规模，中医药研究在其中占据重要地位，《中国中药杂志》是最主要的发文期刊，发文 120 篇；中国中医科学院是发文最多的机构，发文 338 篇；该机构的谢雁鸣发文 250 篇，是发文最多的作者。通过知识图谱分析国内真实世界研究相关文献的发展脉络，有助于临床医生和研究人员更好地了解真实世界研究在国内的发展变化。.
Keywords: bibliometric analysis; knowledge map; real-world research.