Exploring the structure-function relationship in a hypothetical membrane protein from a nucleotide sequence

Biochem Mol Biol Educ. 2021 Jul;49(4):652-657. doi: 10.1002/bmb.21524. Epub 2021 Apr 29.

Abstract

An educational activity is proposed that uses software for proteomic analysis and databases available for free on the Internet to estimate the structure and function of a hypothetical protein from its coding nucleotide sequence. This bioinformatics activity is recommended for integrated introductory courses that address the structure function relationship in proteins.

Keywords: bioinformatics; protein structure; undergraduate.

MeSH terms

  • Base Sequence
  • Computational Biology / education*
  • Computational Biology / methods*
  • Humans
  • Membrane Proteins / chemistry*
  • Membrane Proteins / metabolism*
  • Sequence Analysis, DNA / methods*
  • Software*
  • Structure-Activity Relationship

Substances

  • Membrane Proteins