IR780-based nanomaterials for cancer imaging and therapy

Long Wang; Chengcheng Niu

doi:10.1039/d1tb00407g

IR780-based nanomaterials for cancer imaging and therapy

J Mater Chem B. 2021 May 26;9(20):4079-4097. doi: 10.1039/d1tb00407g.

Authors

Long Wang¹, Chengcheng Niu²

Affiliations

¹ Research Center of Ultrasonography, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China. niuchengcheng@csu.edu.cn and Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
² Research Center of Ultrasonography, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China. niuchengcheng@csu.edu.cn and Department of Ultrasound Diagnosis and Research Center of Ultrasonography, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.

PMID: 33912889
DOI: 10.1039/d1tb00407g

Abstract

IR780, a small molecule with a strong optical property and excellent photoconversion efficiency following near infrared (NIR) irradiation, has attracted increasing attention in the field of cancer treatment and imaging. This review is focused on different IR780-based nanoplatforms and the application of IR780-based nanomaterials for cancer bioimaging and therapy. Thus, this review summarizes the overall aspects of IR780-based nanomaterials that positively impact cancer biomedical applications.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Humans
Indoles / chemistry
Indoles / pharmacology*
Infrared Rays
Nanostructures / chemistry*
Neoplasms / diagnostic imaging*
Neoplasms / drug therapy*

Substances

2-(2-(2-chloro-3-((1,3-dihydro-3,3-dimethyl-1-propyl-2H-indol-2-ylidene)ethylidene)-1-cyclohexen-1-yl)ethenyl)-3,3-dimethyl-1-propylindolium
Indoles