Brain-responsive neurostimulation in adult-onset rasmussen's encephalitis

Anteneh M Feyissa; Alaa S Mohamed; William O Tatum; Alana S Campbell; A Sebastian Lopez-Chiriboga

doi:10.1016/j.ebr.2021.100445

Brain-responsive neurostimulation in adult-onset rasmussen's encephalitis

Epilepsy Behav Rep. 2021 Mar 29:15:100445. doi: 10.1016/j.ebr.2021.100445. eCollection 2021.

Authors

Anteneh M Feyissa^{1

2}, Alaa S Mohamed^{1

2}, William O Tatum^{1

2}, Alana S Campbell^{1

2}, A Sebastian Lopez-Chiriboga^{1

2}

Affiliations

¹ Mayo Clinic Florida, Jacksonville, FL, United States.
² Department of Neurology, United States.

Abstract

Epilepsy associated with Rasmussen's encephalitis (RE) is highly resistant to standard therapy and continues to present a therapeutic challenge. While epilepsy surgery remains the most effective management for patients with drug-resistant focal epilepsy and RE, hemispherotomy may debilitating consequences on adult patients. Here we present the outcome of a 32-year-old woman with adult-onset Rasmussen's, who was treated with brain-responsive neurostimulation (RNS) after failure of several immunotherapeutic and anti-seizure medications.

Keywords: RNS; Rasmussen's encephalitis; Responsive neurostimulation; drug-resistant epilepsy.

Publication types

Case Reports