Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study

Int J Appl Basic Med Res. 2021 Apr-Jun;11(2):90-94. doi: 10.4103/ijabmr.IJABMR_391_19. Epub 2021 Apr 8.

Abstract

Context: The adverse effects associated with traditional adjunctive chemical agents in the management of gingivitis has stimulated research into search for alternate molecules including herbal products. Aims-To compare the effects of oral curcumin gel as an adjunct to scaling and root planing (SRP) with the effects achieved by SRP alone by assessing their effects on plaque, gingival inflammation and gingival bleeding.

Materials and methods: Sixty patients in the age group of 20-60 years were recruited employing inclusion and exclusion criteria. Study population was randomly divided into two groups. Group A-test group was instructed to use twice daily the experimental curcumin gel after initial SRP. Group B-control group received only SRP. Parameters recorded were plaque index (PI), gingival index (GI) and sulcus bleeding index (SBI) on day 0 (baseline), days 7, 14, and 21 along with subjective assessment of any reported untoward side effect. Data was analyzed statistically.

Results: The PI, GI and SBI decreased in both the test group and control group from day 0 to day 21 consecutively. Intergroup comparison shows that all the parameters were statistically significant in Group A (P < 0.001) as compared to Group B.

Conclusion: Curcumin gel has significant antiplaque and anti-inflammatory effect in the treatment of gingivitis and can be effectively employed as an adjunct to SRP.

Keywords: Curcumin gel; gingivitis; scaling and root planing.