Antibody Response to Coronavirus Disease 2019 (COVID-19) Messenger RNA Vaccination in Pregnant Women and Transplacental Passage Into Cord Blood

Malavika Prabhu; Elisabeth A Murphy; Ashley C Sukhu; Jim Yee; Sunidhi Singh; Dorothy Eng; Zhen Zhao; Laura E Riley; Yawei J Yang

doi:10.1097/AOG.0000000000004438

Antibody Response to Coronavirus Disease 2019 (COVID-19) Messenger RNA Vaccination in Pregnant Women and Transplacental Passage Into Cord Blood

Obstet Gynecol. 2021 Aug 1;138(2):278-280. doi: 10.1097/AOG.0000000000004438.

Authors

Malavika Prabhu¹, Elisabeth A Murphy, Ashley C Sukhu, Jim Yee, Sunidhi Singh, Dorothy Eng, Zhen Zhao, Laura E Riley, Yawei J Yang

Affiliation

¹ Department of Obstetrics and Gynecology and the Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, the Laboratory of Molecular Neuro-oncology, the Rockefeller University, and the Department of Pathology and Laboratory Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, New York.

Abstract

Coronavirus disease 2019 (COVID-19) vaccination in pregnancy induces a robust maternal immune response, with transplacental antibody transfer detectable in cord blood as early as 16 days after the first dose.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Antibody Formation
COVID-19*
Female
Fetal Blood
Humans
Pregnancy
Pregnancy Complications, Infectious* / prevention & control
Pregnant Women
RNA, Messenger
SARS-CoV-2
Vaccination

Substances

RNA, Messenger