Lignans from Bupleurum marginatum and their antioxidant activity

Nat Prod Res. 2022 Oct;36(19):5016-5021. doi: 10.1080/14786419.2021.1917570. Epub 2021 Apr 28.

Abstract

A new aryltetralin lignan, bupleroid A (1), along with ten known analogues (2-11) were isolated from Bupleurum marginatum. The structures of these isolates were determined by 1D and 2D NMR, HRESIMS, and ECD data analysis. In addition, the DPPH radical scavenging capacities of all compounds were evaluated. Compound 6 exhibited good DPPH radical scavenging activity at a concentration of 50 μM.[Formula: see text].

Keywords: Bupleurum marginatum; DPPH; antioxidant; lignan.

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / pharmacology
  • Bupleurum* / chemistry
  • Lignans* / chemistry
  • Lignans* / pharmacology
  • Molecular Structure
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology

Substances

  • Antioxidants
  • Lignans
  • Plant Extracts