Association of Age and Sex with Metabolic Syndrome in Taiwanese Adults

Pang-Li Liu; Ming-Yi Hsu; Chao-Chin Hu; Disline Manli Tantoh; Wen-Yu Lu; Oswald Ndi Nfor; Yung-Po Liaw

doi:10.2147/IJGM.S296814

Association of Age and Sex with Metabolic Syndrome in Taiwanese Adults

Int J Gen Med. 2021 Apr 20:14:1403-1411. doi: 10.2147/IJGM.S296814. eCollection 2021.

Authors

Pang-Li Liu¹, Ming-Yi Hsu^{2

3}, Chao-Chin Hu⁴, Disline Manli Tantoh^{5

6}, Wen-Yu Lu⁶, Oswald Ndi Nfor⁶, Yung-Po Liaw^{5

6}

Affiliations

¹ Department of Medical Sociology and Social Work, Chung Shan Medical University, Taichung, 40201, Taiwan.
² Department of Nursing, Chung Shan Medical University, Taichung, 40201, Taiwan.
³ Department of Nursing, Chung Shan Medical University Hospital, Taichung, 40201, Taiwan.
⁴ Department of Medical Applied Chemistry, Chung Shan Medical University, Taichung, 40201, Taiwan.
⁵ Department of Medical Imaging, Chung Shan Medical University Hospital, Taichung, 40201, Taiwan.
⁶ Department of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung, 40201, Taiwan.

Abstract

Objective: This study aimed to investigate the association of age and sex with metabolic syndrome (MS) in Taiwanese adults.

Methods: We extracted information of 4307 men and 4783 women aged 30-70 from the Taiwan Biobank.

Results: The interaction between age and sex on MS was significant (p-value = 0.0001). After stratification by sex, men and women aged 50-70 years (reference: 30≤age<50 years) had a higher risk of MS. The odds ratio (OR), 95% confidence interval (CI) was 2.316, 1.936-2.772 in men and 3.101, 2.561-3.754 in women. After stratification by age, men aged 50-70 years had a lower risk of MS compared to women (OR, 95% CI = 0.713, 0.598-0.851).

Conclusion: The interaction between age and sex on MS was significant. Sex-wise, both men and women aged 50-70 years had a higher likelihood of MS. Age-wise, men aged 50-70 years had a lower risk of MS compared to women.

Keywords: Taiwan Biobank; age; metabolic syndrome; sex.

Grants and funding

The Ministry of Science and Technology (MOST), Taiwan sponsored this work (MOST 109-2121-M-040-002).