Obesity: Overview of Weight Management

Meetal Mehta; Nawfal W Istfan; Caroline M Apovian

doi:10.1016/j.eprac.2021.04.001

Obesity: Overview of Weight Management

Endocr Pract. 2021 Jun;27(6):626-635. doi: 10.1016/j.eprac.2021.04.001. Epub 2021 Apr 24.

Authors

Meetal Mehta¹, Nawfal W Istfan², Caroline M Apovian²

Affiliations

¹ Brigham and Women's Hospital, Center for Weight Management and Wellness, Section of Endocrinology, Diabetes and Hypertension, Harvard Medical School, Boston, Massachusetts. Electronic address: mmehta8@bwh.harvard.edu.
² Brigham and Women's Hospital, Center for Weight Management and Wellness, Section of Endocrinology, Diabetes and Hypertension, Harvard Medical School, Boston, Massachusetts.

PMID: 33901648
DOI: 10.1016/j.eprac.2021.04.001

Abstract

Introduction: Obesity is a chronic illness that requires a multifaceted personalized treatment approach.

Methods & findings: Using current guidelines and recent studies in weight management, this article reviews the multiple components of weight management: lifestyle intervention (dietary intervention, physical activity, and behavioral interventions), pharmacotherapy, endoscopic procedures, and surgical procedures. This review briefly discusses specific diets and dietary strategies, compensatory mechanisms acting against weight loss, recent changes to Food and Drug Administration approved antiobesity medications, and technological advances in weight management delivery.

Conclusion: Current literature is lacking large studies on the safety and efficacy of combination therapies involving pharmacotherapy plus 1 or more procedures.

Keywords: obesity; weight loss; weight management.

Publication types

Review

MeSH terms

Anti-Obesity Agents* / therapeutic use
Body Weight
Humans
Life Style
Obesity* / therapy
Weight Loss

Substances

Anti-Obesity Agents